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Episodic Shaking & Facial Twitching in a Terrier

A dog was emergently presented for neurologic evaluation following a recent onset of episodic shaking and facial twitching. Follow this patient’s case and watch a video of the presentation to uncover the diagnosis.

Neurology|Peer Reviewed

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Sarcoma in Animals and Humans

Man vs man’s best friend—view a side-by-side sarcoma case in a dog and in a human.

Oncology|Peer Reviewed

Infectious Disease

Research Note: Novel Protoparvovirus in Cats

Research Note: Canine Cytochrome B Blood Mutations

Contaminated Biocides

Inhibition of Type I Feline Coronavirus Infection by Itraconazole

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               <div id="dfp-desktop-header-ad" style="height: 90px; width: 728px; background: #f1f1f1; color: #bcbcbc; display: flex; justify-content: center; align-items: center; flex-direction: column;">Leaderboard Ad</div>
            </div>
         </div>
      </div>
      <div identification="main-header" class="col-12">
         <div class="col-12">
            <div class="relative flex items-center justify-center border-bottom border-bottom-light-gry border-top border-top-light-gry bg-white">
               <div identification="responsive-header" class="relative flex transition-all col-hdr header-height">
                  <div identification="mobile-menu-signed-in" class="display-none">
                     <div identification="menu-button" class="mn-display-none xs-flex sm-flex flex-row items-center justify-center border-1 hover-bg-light-gry transition-all icon a-hard-height-for-button">
                        <i component="icon" identification="menu-icon" class="fa fa-bars " aria-hidden="true" style="" v-bind:class="{  }"></i>
                     </div>
                     <div identification="menu-overlay" class="absolute display-none-important flex flex-column transition-all col-12 overlay-black" style="top: 4.9rem; left: 0; height: 100vh;"></div>
                     <div identification="menu-dropdown" class="absolute z1 display-none-important flex flex-column md-col-4 sm-col-6 xs-col-9 transition-all slide-out-left" style="top: 4.9rem; left: 0;">
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">Events</p>
                        </a>
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">Career Center</p>
                        </a>
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">Topics</p>
                        </a>
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">CE</p>
                        </a>
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">Practice Solutions</p>
                        </a>
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">Algorithms</p>
                        </a>
                        <a href="#" class="nrw-display-none center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">My Favorites</p>
                        </a>
                        <a href="#" class="nrw-display-none center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">My Account</p>
                        </a>
                        <div identification="logout" class="nrw-display-none center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">Sign Out</p>
                        </div>
                        <div identification="close-button" class="inline-block border-box center col-12 border-3 border-bottom border-primary--dark bg-primary hover-bg-primary--dark font-size-1 color-white bold caps text-decoration-none line-height-4 transition-bg cursor-pointer btn-padding-filled a-hard-height-for-button">Close</div>
                     </div>
                  </div>
                  <div identification="mobile-menu-signed-out" class="display-none">
                     <div identification="menu-button" class="mn-display-none xs-flex sm-flex flex-row items-center justify-center border-1 hover-bg-light-gry transition-all icon a-hard-height-for-button">
                        <i component="icon" identification="menu-icon" class="fa fa-bars " aria-hidden="true" style="" v-bind:class="{  }"></i>
                     </div>
                     <div identification="menu-overlay" class="absolute  display-none-important flex flex-column transition-all col-12 overlay-black" style="top: 4.9rem; left: 0; height: 100vh;"></div>
                     <div identification="menu-dropdown" class="absolute z1 display-none-important flex flex-column md-col-4 sm-col-6 xs-col-9 transition-all slide-out-left" style="top: 4.9rem; left: 0;">
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">Events</p>
                        </a>
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">Career Center</p>
                        </a>
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">Topics</p>
                        </a>
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">CE</p>
                        </a>
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">Practice Solutions</p>
                        </a>
                        <a href="#" class="center col-12 border-1 border-right border-bottom border-light-gry hover-bg-bright-gry bg-white font-size-1 color-text bold text-decoration-none line-height-4 transition-all btn-padding-filled a-hard-height-for-button">
                           <p class="m0 p0 font-size-2 bold sans line-height-2">Algorithms</p>
                        </a>
                        <div identification="close-button" class="inline-block border-box center col-12 border-3 border-bottom border-primary--dark bg-primary hover-bg-primary--dark font-size-1 color-white bold caps text-decoration-none line-height-4 transition-bg cursor-pointer btn-padding-filled a-hard-height-for-button">Close</div>
                     </div>
                  </div>
                  <div class="flex flex-auto items-center xs-justify-center sm-justify-center mn-justify-start px1-5 color-text sans">
                     <a class="block" href="#" identification="home-button">
                        <h1 class="m0 p0 line-height-1 flex items-center justify-center">
                           <img src="https://www.cliniciansbrief.com/themes/custom/brief/images/cb/logo.svg" alt="Clinician's Brief" style="width: 155px; height: 24px;">
                        </h1>
                     </a>
                  </div>
                  <a href="#" class="xs-display-none sm-display-none mn-flex items-center justify-center px1-5 py1 hover-color-secondary color-text sans text-decoration-none transition-all">
                     <p class="m0 p0 font-size-2 bold sans line-height-2">Events</p>
                  </a>
                  <a href="#" class="xs-display-none sm-display-none mn-flex items-center justify-center px1-5 py1 hover-color-secondary color-text sans text-decoration-none transition-all">
                     <p class="m0 p0 font-size-2 bold sans line-height-2">Career Center</p>
                  </a>
                  <a href="#" class="xs-display-none sm-display-none mn-flex items-center justify-center px1-5 py1 hover-color-secondary color-text sans text-decoration-none transition-all">
                     <p class="m0 p0 font-size-2 bold sans line-height-2">Topics</p>
                  </a>
                  <a href="#" class="xs-display-none sm-display-none mn-flex items-center justify-center px1-5 py1 hover-color-secondary color-text sans text-decoration-none transition-all">
                     <p class="m0 p0 font-size-2 bold sans line-height-2">CE</p>
                  </a>
                  <a href="#" class="xs-display-none sm-display-none mn-flex items-center justify-center px1-5 py1 hover-color-secondary color-text sans text-decoration-none transition-all">
                     <p class="m0 p0 font-size-2 bold sans line-height-2">Practice Solutions</p>
                  </a>
                  <a href="#" class="xs-display-none sm-display-none mn-flex items-center justify-center px1-5 py1 hover-color-secondary color-text sans text-decoration-none transition-all">
                     <p class="m0 p0 font-size-2 bold sans line-height-2">Algorithms</p>
                  </a>
                  <div identification="header-search-icon" class="flex flex-auto items-center justify-center xs-hover-bg-light-gry sm-hover-bg-light-gry mn-hover-bg-white xs-hover-color-text sm-hover-color-text mn-hover-color-primary transition-all cursor-pointer" style="max-width: 4.8rem; width: 4.8rem;">
                     <i component="icon" identification="search-icon" class="fa fa-search " aria-hidden="true" style="" v-bind:class="{  }"></i>
                  </div>
               </div>
            </div>
         </div>
         <div class="bg-bright-gry" style="height: 49px;">
            <div identification="signed-in" class="display-none col-12 fade-in">
               <div class="relative flex items-center justify-center border-bottom border-light-gry bg-bright-gry z3">
                  <div class="flex col-hdr mn-border-left border-light-gry a-hard-height-for-button">
                     <div class="xs-display-none sm-display-none mn-flex xs-flex-auto sm-flex-auto items-center xs-justify-center sm-justify-center md-justify-start md-shrink-1 md-col-12 px1-5 py1   xs-border-none sm-border-none color-text sans"></div>
                     <a href="#" class="xs-display-none sm-display-none flex nrw-flex flex-auto items-center justify-center m0 p0 px1-5 py1 border-left border-light-gry border-none bg-none hover-bg-light-gryfont-size-2 color-text sans text-decoration-none line-height-2 transition-all cursor-pointer">
                     <i component="icon" class="fa fa-list-ul mr1" aria-hidden="true" style="" v-bind:class="{  }"></i>
                     My Favorites
                     </a>
                     <div class="relative flex flex-auto flex-column items-center justify-center border-left border-light-gry hover-bg-light-gry transition-all cursor-pointer">
                        <button identification="share-button" class="flex flex-auto items-center justify-center col-12 px1-5 py1 border-none bg-none font-size-2 color-text sans text-decoration-none line-height-2">
                        <i component="icon" class="fa fa-share-alt mr1" aria-hidden="true" style="" v-bind:class="{  }"></i>
                        Share
                        </button>
                        <div identification="share-dropdown" class="absolute top-100 right-0 flex-column md-col-12 xs-col-auto nrw-col-auto h-0 bg-white overflow-hidden transition-all z4">
                           <a href="#" target="_blank" class="flex items-center justify-start col-12 border border-1 border-right border-light-gry border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
                              <div class="flex items-end justify-end bg-facebook-dark-blue" style="width:48px; height:48px;">
                                 <i component="icon" class="fa fa-facebook mr1 font-size-h2 color-white" aria-hidden="true" style="margin-bottom: -3px;" v-bind:class="{  }"></i>
                              </div>
                              <p class="m0 p0 pr5 pl1-5 font-size-2 sans line-height-2" style="width:calc(100% - 48px);">Facebook</p>
                           </a>
                           <a href="#" target="_blank" class="flex items-center justify-start col-12 border-1 border-right border-bottom border-left border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
                              <div class="flex items-center justify-center bg-twitter-blue" style="width:48px; height:48px;">
                                 <i component="icon" class="fa fa-twitter font-size-h3 color-white" aria-hidden="true" style="" v-bind:class="{  }"></i>
                              </div>
                              <p class="m0 p0 pr5 pl1-5 font-size-2 sans line-height-2" style="width:calc(100% - 48px);">Twitter</p>
                           </a>
                           <a href="#" target="_blank" class="flex items-center justify-start col-12 border-1 border-right border-bottom border-left border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
                              <div class="flex items-center justify-center" style="width:48px; height:48px; background: #0077b5">
                                 <i component="icon" class="fa fa-linkedin font-size-h3 color-white" aria-hidden="true" style="" v-bind:class="{  }"></i>
                              </div>
                              <p class="m0 p0 pr5 pl1-5 font-size-2 sans line-height-2" style="width:calc(100% - 48px);">LinkedIn</p>
                           </a>
                           <a href="#" target="_blank" class="flex items-center justify-start col-12 border-1 border-right border-bottom border-left border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
                              <div class="flex items-center justify-center bg-red border-1 border-bottom border-white" style="width:48px; height:48px;">
                                <i class="fa fa-envelope-open font-size-h4 color-white" aria-hidden="true" style="" v-bind:class="{  }"></i>
                                
                              </div>
                              <p class="m0 p0 pr5 pl1-5 font-size-2 sans line-height-2" style="width:calc(100% - 48px);">Email</p>
                           </a>
                        </div>
                     </div>
                     <a href="#" class="xs-display-none sm-display-none flex nrw-flex flex-auto flex-auto items-center justify-center m0 p0 px1-5 py1 border-left border-light-gry border-none hover-bg-light-gry font-size-2 color-text sans text-decoration-none line-height-2 transition-all cursor-pointer">
                     <i component="icon" class="fa fa-user mr1" aria-hidden="true" style="" v-bind:class="{  }"></i>
                     My Account
                     </a>
                     <span identification="logout" class="xs-display-none sm-display-none flex nrw-flex flex-auto flex-auto items-center justify-center m0 p0 px1-5 py1 border-right border-left border-light-gry border-none hover-bg-light-gry font-size-2 color-text sans text-decoration-none line-height-2 transition-all cursor-pointer">
                     Sign Out
                     </span>
                  </div>
                  <div identification="close-share" class="absolute flex flex-column col-12 display-none-important" style="top: 4.9rem; left: 0; height: 100vh;"></div>
                  <div identification="close-years" class="absolute flex flex-column col-12 display-none-important" style="top: 4.9rem; left: 0; height: 100vh;"></div>
                  <div identification="close-issues" class="absolute flex flex-column col-12 display-none-important" style="top: 4.9rem; left: 0; height: 100vh;"></div>
                  <div identification="close-toc" class="absolute flex flex-column col-12 display-none-important" style="top: 4.9rem; left: 0; height: 100vh;"></div>
               </div>
            </div>
            <div identification="signed-out" class="display-none col-12 fade-in">
               <div class="relative flex items-center justify-center border-bottom border-light-gry bg-bright-gry z3">
                  <div class="flex col-hdr mn-border-left border-light-gry a-hard-height-for-button">
                     <a identification="home-button" href="#" class="xs-display-none sm-display-none mn-flex flex-auto items-center justify-center m0 p0 px1-5 py1 hover-bg-light-gry font-size-2 color-text sans sans text-decoration-none line-height-2 transition-all cursor-pointer u-no-select">
                     <i component="icon" class="fa fa-home xs-m0 sm-mr0-5" aria-hidden="true" style="" v-bind:class="{  }"></i>
                     Home
                     </a>
                     <div class="xs-display-none sm-display-none mn-flex xs-flex-auto sm-flex-auto items-center xs-justify-center sm-justify-center md-justify-start md-shrink-1 md-col-12 px1-5 py1 md-border-left md-border-left md-border-light-gry xs-border-none sm-border-none color-text sans u-no-select"></div>
                     <div class="relative xs-display-none sm-display-none nrw-flex flex-auto flex-column items-center justify-center border-left border-light-gry hover-bg-light-gry transition-all cursor-pointer">
                        <button identification="share-button" class="flex flex-auto items-center justify-center col-12 px1-5 py1 border-none bg-none font-size-2 color-text sans text-decoration-none line-height-2">
                        <i component="icon" class="fa fa-share-alt mr1" aria-hidden="true" style="" v-bind:class="{  }"></i>
                        Share
                        </button>
                        <div identification="share-dropdown" class="absolute top-100 right-0 flex-column md-col-12 xs-col-auto mn-col-auto h-0 bg-white overflow-hidden transition-all z4">
                           <a href="#" target="_blank" class="flex items-center justify-start col-12 border border-1 border-right border-light-gry border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
                              <div class="flex items-end justify-end bg-facebook-dark-blue" style="width:48px; height:48px;">
                                 <i component="icon" class="fa fa-facebook mr1 font-size-h2 color-white" aria-hidden="true" style="margin-bottom: -3px;" v-bind:class="{  }"></i>
                              </div>
                              <p class="m0 p0 pr5 pl1-5 font-size-2 sans line-height-2" style="width:calc(100% - 48px);">Facebook</p>
                           </a>
                           <a href="#" target="_blank" class="flex items-center justify-start col-12 border-1 border-right border-bottom border-left border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
                              <div class="flex items-center justify-center bg-twitter-blue" style="width:48px; height:48px;">
                                 <i component="icon" class="fa fa-twitter font-size-h3 color-white" aria-hidden="true" style="" v-bind:class="{  }"></i>
                              </div>
                              <p class="m0 p0 pr5 pl1-5 font-size-2 sans line-height-2" style="width:calc(100% - 48px);">Twitter</p>
                           </a>
                           <a href="#" target="_blank" class="flex items-center justify-start col-12 border-1 border-right border-bottom border-left border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
                              <div class="flex items-center justify-center" style="width:48px; height:48px; background: #0077b5">
                                 <i component="icon" class="fa fa-linkedin font-size-h3 color-white" aria-hidden="true" style="" v-bind:class="{  }"></i>
                              </div>
                              <p class="m0 p0 pr5 pl1-5 font-size-2 sans line-height-2" style="width:calc(100% - 48px);">LinkedIn</p>
                           </a>
                           <a href="#" target="_blank" class="flex items-center justify-start col-12 border-1 border-right border-bottom border-left border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
                              <div class="flex items-center justify-center bg-red border-1 border-bottom border-white" style="width:48px; height:48px;">
                                 <i component="icon" class="fa fa-envelope font-size-h4 color-white" aria-hidden="true" style="" v-bind:class="{  }"></i>
                              </div>
                              <p class="m0 p0 pr5 pl1-5 font-size-2 sans line-height-2" style="width:calc(100% - 48px);">Email</p>
                           </a>
                        </div>
                     </div>
                     <div class="flex flex-auto items-center justify-center px1-5 py1 border-left border-light-gry hover-bg-light-gry color-text sans transition-all cursor-pointer u-no-select">
                        <a href="#" class="flex flex-auto items-center justify-center m0 p0 font-size-2 color-text sans text-decoration-none line-height-2">
                        <i component="icon" class="fa fa-user mr1" aria-hidden="true" style="" v-bind:class="{  }"></i>
                        Create Account
                        </a>
                     </div>
                     <a href="#" identification="sign-in-button" class="flex flex-auto items-center justify-center bg-accent hover-bg-accent--dark font-size-2 color-white sans text-decoration-none line-height-2 transition-all cursor-pointer btn-padding-filled">
                     Sign In
                     </a>
                  </div>
                  <div identification="close-share" class="absolute flex flex-column col-12 display-none-important" style="top: 4.9rem; left: 0; height: 100vh;"></div>
                  <div identification="close-years" class="absolute flex flex-column col-12 display-none-important" style="top: 4.9rem; left: 0; height: 100vh;"></div>
                  <div identification="close-issues" class="absolute flex flex-column col-12 display-none-important" style="top: 4.9rem; left: 0; height: 100vh;"></div>
                  <div identification="close-toc" class="absolute flex flex-column col-12 display-none-important" style="top: 4.9rem; left: 0; height: 100vh;"></div>
               </div>
            </div>
         </div>
      </div>
   </div>
   <div id="fluid-banner-slot"></div>
   <div identification="header-search--overlay" class="fixed display-none" style="height:100%;width:100%;top:0;left:0;background-color:transparent;z-index:1"></div>
   <div identification="header-search" class="bg-secondary relative flex justify-center items-center py1-5">
      <div identification="search-bar-animation" class="flex justify-center items-center col-main">
         <input type="hidden" id="search-filter-media" value="">
         <div class="relative xs-display-none sm-display-none md-flex flex-auto flex-column items-center justify-center bg-secondary hover-bg-secondary--dark transition-all cursor-pointer a-hard-height-for-button zh5">
            <button identification="search-dropdown-button" class="flex flex-auto items-center justify-center px1-5 py1 border-none bg-none font-size-2 color-white sans text-decoration-none line-height-2" style="min-width: 130px; width: 130px;">
               <div identification="search-decision">
                  All Content
               </div>
               <i component="icon" class="fa fa-chevron-down ml1 color-white" aria-hidden="true" style="" v-bind:class="{  }"></i>
            </button>
            <div identification="search-options" class="absolute top-100 left-0 flex-column col-12 bg-white overflow-hidden transition-all z4" style="height:0">
               <div identification="search-all-content" class="flex items-center justify-start col-12 border-1 border-right border-left border-bottom border-top border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
                  <div class="px1-5">All Content</div>
               </div>
               <div identification="search-articles" class="flex items-center justify-start col-12 border-1 border-right border-left border-bottom border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
                  <div class="px1-5">Articles</div>
               </div>
               <div identification="search-quizzes" class="flex items-center justify-start col-12 border-1 border-right border-left border-bottom border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
                  <div class="px1-5">Quizzes</div>
               </div>
               <div identification="search-videos" class="flex items-center justify-start col-12 border-1 border-right border-left border-bottom border-light-gry hover-bg-bright-gry color-text sans text-decoration-none transition-all a-hard-height-for-button">
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