</head> <body style="-ms-text-size-adjust:100%;-webkit-text-size-adjust:100%;margin:0;min-width:100%;padding:0;width:100%" data-bg-color="#e8e8e8" bgcolor="#e8e8e8">
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Oral methadone is an effective pain control option for humans, but a difference in liver metabolism means it’s not a useful option in dogs due to poor bioavailability. Enter: A new study that uses medications we already have to manipulate liver enzymes and enhance the pharmacokinetics of this powerful oral opioid. Researchers combined oral methadone with fluconazole and naltrexone in two different dosing protocols for post-operative ovariohysterectomy patients, then performed pain scoring to assess analgesia. Did this combination have clinical efficacy?

Get all the details here on how combining oral methadone with other medications in your pharmacy could give you a new pain control option in your canine patients.

https://www.cliniciansbrief.com/article/changing-methadone-metabolism-prolong-analgesia?utm_medium=email&utm_source=Clinician%27s+Brief+Newsletter&utm_campaign=Online+210921 Anesthesiology {amp} Pain Management {{frompagetopatient::featured_card_cb_primary_topic_remove}} {{frompagetopatient::featured_card_qualification}} {{frompagetopatient::featured_card_qualification_remove}} A Wealth of Cat Content in One Spot {{frompagetopatient::card_2_image}}

If you're looking for information about feline health, look no further than this resource library. Start exploring.

https://www.cliniciansbrief.com/feline-portal?utm_medium=email&utm_source=Clinician%27s+Brief+Newsletter&utm_campaign=Online+210921 {{frompagetopatient::card_2_cb_primary_topic}} {{frompagetopatient::card_2_cb_primary_topic_remove}} Sponsored {{frompagetopatient::card_2_qualification_remove}} Nasal Insufflation: Adequate O2 Delivery? {{frompagetopatient::card_3_image}}

A recent study compared the amount of oxygen reaching the patient to the flowmeter setting. Get the results here.

https://www.cliniciansbrief.com/article/nasal-oxygen-insufflation-limitations-clinical-applicability?utm_medium=email&utm_source=Clinician%27s+Brief+Newsletter&utm_campaign=Online+210921 Emergency Medicine {amp} Critical Care {{frompagetopatient::card_3_cb_primary_topic_remove}} {{frompagetopatient::card_3_qualification}} {{frompagetopatient::card_3_qualification_remove}} Parasite Prevalence at Dog Parks {{frompagetopatient::card_4_image}}

Dog parks provide a place to play and socialize with other pets. Discover which parasites are most prevalent and how we can minimize risks.

https://www.cliniciansbrief.com/article/parasite-risk-dog-parks?utm_medium=email&utm_source=Clinician%27s+Brief+Newsletter&utm_campaign=Online+210921 Parasitology {{frompagetopatient::card_4_cb_primary_topic_remove}} {{frompagetopatient::card_4_qualification}} {{frompagetopatient::card_4_qualification_remove}} Ease Delivery of Essential Fatty Acids {{frompagetopatient::card_5_image}}

Owners get their pets more essential fatty acids like omega-3s and omega-6s when it’s already in their kibble as opposed to capsules. Try these options for allergic pets.

https://www.hillsvet.com/products/dog-food/pd-zd-canine-dry {{frompagetopatient::card_5_cb_primary_topic}} {{frompagetopatient::card_5_cb_primary_topic_remove}} Sponsored {{frompagetopatient::card_5_qualification_remove}} {{frompagetopatient::300x250_image}} {{frompagetopatient::300x250_url}}
Discover how a new method of administration may help veterinary patients.
Clinician's Brief
From Page to Patient
Tuesday, September 21, 2021
Can You Give Your Canine Patients Better Analgesia with Medications You Already Have?
Anesthesiology {amp} Pain Management
From the page...
<p>Oral methadone is an effective pain control option for humans, but a difference in liver metabolism means it’s not a useful option in dogs due to poor bioavailability. Enter: A new study that uses medications we already have to manipulate liver enzymes and enhance the pharmacokinetics of this powerful oral opioid. Researchers combined oral methadone with fluconazole and naltrexone in two different dosing protocols for post-operative ovariohysterectomy patients, then performed pain scoring to assess analgesia. Did this combination have clinical efficacy?</p>
...To your patients
<p>Get all the details here on how combining oral methadone with other medications in your pharmacy could give you a new pain control option in your canine patients.</p>
Read More
A Wealth of Cat Content in One Spot
<p>If you're looking for information about feline health, look no further than this resource library. Start exploring.</p>
Sponsored
Nasal Insufflation: Adequate O2 Delivery?
<p><span style="background-color: transparent; color: rgb(0, 0, 0);">A recent study compared the amount of oxygen reaching the patient to the flowmeter setting. Get the results here.</span></p>
Emergency Medicine {amp} Critical Care
Parasite Prevalence at Dog Parks
<p><span style="background-color: transparent; color: rgb(0, 0, 0);">Dog parks provide a place to play and socialize with other pets. Discover which parasites are most prevalent and how we can minimize risks.</span></p>
Parasitology
Ease Delivery of Essential Fatty Acids
<p><span style="background-color: transparent; color: rgb(0, 0, 0);">Owners get their pets more essential fatty acids like omega-3s and omega-6s when it’s already in their kibble as opposed to capsules. Try these options for allergic pets.</span></p>
Sponsored
Looking for more pearls to
put into practice?
Browse the whole From Page to Patient
collection here.
</head> <body style="-ms-text-size-adjust:100%;-webkit-text-size-adjust:100%;margin:0;min-width:100%;padding:0;width:100%" data-bg-color="#e8e8e8" bgcolor="#e8e8e8">
Discover how a new method of administration may help veterinary patients.
Clinician's Brief
From Page to Patient
Tuesday, September 21, 2021
Can You Give Your Canine Patients Better Analgesia with Medications You Already Have?
Anesthesiology {amp} Pain Management
From the page...
<p>Oral methadone is an effective pain control option for humans, but a difference in liver metabolism means it’s not a useful option in dogs due to poor bioavailability. Enter: A new study that uses medications we already have to manipulate liver enzymes and enhance the pharmacokinetics of this powerful oral opioid. Researchers combined oral methadone with fluconazole and naltrexone in two different dosing protocols for post-operative ovariohysterectomy patients, then performed pain scoring to assess analgesia. Did this combination have clinical efficacy?</p>
...To your patients
<p>Get all the details here on how combining oral methadone with other medications in your pharmacy could give you a new pain control option in your canine patients.</p>
Read More
A Wealth of Cat Content in One Spot
<p>If you're looking for information about feline health, look no further than this resource library. Start exploring.</p>
Sponsored
Nasal Insufflation: Adequate O2 Delivery?
<p><span style="background-color: transparent; color: rgb(0, 0, 0);">A recent study compared the amount of oxygen reaching the patient to the flowmeter setting. Get the results here.</span></p>
Emergency Medicine {amp} Critical Care
Parasite Prevalence at Dog Parks
<p><span style="background-color: transparent; color: rgb(0, 0, 0);">Dog parks provide a place to play and socialize with other pets. Discover which parasites are most prevalent and how we can minimize risks.</span></p>
Parasitology
Ease Delivery of Essential Fatty Acids
<p><span style="background-color: transparent; color: rgb(0, 0, 0);">Owners get their pets more essential fatty acids like omega-3s and omega-6s when it’s already in their kibble as opposed to capsules. Try these options for allergic pets.</span></p>
Sponsored
Looking for more pearls to
put into practice?
Browse the whole From Page to Patient
collection here.