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All About Apoquel
(oclacitinib tablet)
What's a JAK Inhibitor?
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Just 5 years ago, a completely new class of drug, the Janus kinase (JAK) inhibitor, was introduced to treat allergic dermatitis in dogs. Since that time, Apoquel (the first and only veterinary JAK inhibitor) has been prescribed to treat allergic and atopic dermatitis in over 7 million dogs<sup>1</sup>, giving pet owners an effective alternative to corticosteriods. However, with widespread use of a new drug, and especially a totally new class of drug, there is no historical frame of reference around experiences with short‑or‑long term use. This sometimes leads to misunderstandings or bias based on only a few personal{nbs}experiences.
We've brought together a roundtable of dermatologists, general practitioners, and an oncologist to share their experiences and discuss the facts of using Apoquel.
{pb10}{subhead primary}Learn how 5 years of pharmacovigilance data have{nbs}demonstrated:{/subhead}{/pb10}
- Apoquel is performing similar to pre-approval safety and efficacy studies.
- Pharmacovigelance data has not demonstrated new safety signals
- No causal relationship between administration of JAK inhibitors and development of neoplastic{nbs}conditions
- Use of Apoquel has not shown an increased risk for urinary tract infections (UTI)
- Use of Apoquel with common parasiticides, antibiotics, and vaccines is considered{nbs}safe
- Use of Apoquel has not been evaluated with other systemic immunosuppresants, such as corticosteroids and cyclosporine
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https://www.cliniciansbrief.com/article/clinicians-forum-expert-views-roundtable-apoquel
Read the discussion
Get Details
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INDICATIONS FOR APOQUEL (oclacitinib tablet)
Control of pruritus associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age.
IMPORTANT SAFETY INFORMATION FOR APOQUEL
Do not use APOQUEL in dogs less than 12 months of age or those with serious infections. APOQUEL may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. APOQUEL has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporine. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. APOQUEL has been used safely with many common medications including parasiticides, antibiotics and vaccines. For more information, please see full Prescribing Information.
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Reference: 1. Data on file, Unique Patient Count from Launch, 2019, Zoetis Inc.
